Despite promising early work into the role of immune cells such as eosinophils in adipose tissue (AT) homeostasis, recent findings revealed that elevating the number of eosinophils in AT alone is insufficient for improving metabolic impairments in obese mice. Eosinophils are primarily recognized for their role in allergic immunity and defence against parasitic worms. They have also been detected in AT and appear to contribute to adipose homeostasis and drive energy expenditure, but the underlying mechanisms remain elusive. It has long (...) been recognized that immune cells such as macrophages respond to external signals to regulate adipose homeostasis and energy balance, however, less is known about the relevance of eosinophil activity in AT. As the authors propose in this review, given recent debate over the relative importance of their tissue‐specific abundance, the stage is now set for exploring the functionality and activation states of AT eosinophils. (shrink)

We argue that C. Darwin and more recently W. Hennig worked at times under the simplifying assumption of an eternal biosphere. So motivated, we explicitly consider the consequences which follow mathematically from this assumption, and the infinite graphs it leads to. This assumption admits certain clusters of organisms which have some ideal theoretical properties of species, shining some light onto the species problem. We prove a dualization of a law of T.A. Knight and C. Darwin, and sketch a decomposition result (...) involving the internodons of D. Kornet, J. Metz and H. Schellinx. A further goal of this paper is to respond to B. Sturmfels’ question, “Can biology lead to new theorems?”. (shrink)

The General Data Protection Regulation (GDPR) of the EU confirms the protection of personal data as a fundamental human right and affords data subjects more control over the way their personal information is processed, shared, and analyzed. However, where data are processed by artificial intelligence (AI) algorithms, asserting control and providing adequate explanations is a challenge. Due to massive increases in computing power and big data processing, modern AI algorithms are too complex and opaque to be understood by most data (...) subjects. Articles 15 and 22 of the GDPR provide a modest regulatory framework for automated data processing by, among other things, mandating that data controllers inform data subjects about when it is being used, and its logic and ramifications. Nevertheless, due to the phrasing of the articles and the numerous exceptions they allow, doubts have arisen about their effectiveness. In this paper, we empirically evaluate the quality and effectiveness of AI disclosures as mandated by the GDPR. By means of an online survey (N = 835), we investigated how data subjects expect to be informed about the automated processing of their data. We then conducted a content analysis of the AI disclosures of N = 100 companies and organizations. The combined findings reveal that current GDPR-mandated disclosures do not meet the expectations and needs of data subjects. Explanations drawn up following the guidelines of the generic formulations of the GDPR differ widely and are often vague, incomplete and lack transparency. In our conclusions we identify a path towards standardizing and optimizing AI information notices. (shrink)

Multiarm bandit problems have been used to model the selection of competing scientific theories by boundedly rational agents. In this paper, I define a variable-arm bandit problem, which allows the set of scientific theories to vary over time. I show that Roth-Erev reinforcement learning, which solves multiarm bandit problems in the limit, cannot solve this problem in a reasonable time. However, social learning via preferential attachment combined with individual reinforcement learning which discounts the past, does.

Sender–receiver games, first introduced by David Lewis ([1969]), have received increased attention in recent years as a formal model for the emergence of communication. Skyrms ([2010]) showed that simple models of reinforcement learning often succeed in forming efficient, albeit not necessarily minimal, signalling systems for a large family of games. Later, Alexander et al. ([2012]) showed that reinforcement learning, combined with forgetting, frequently produced both efficient and minimal signalling systems. In this article, I define a ‘dynamic’ sender–receiver game in (...) which the state–action pairs are not held constant over time and show that neither of these two models of learning learn to signal in this environment. However, a model of reinforcement learning with discounting of the past does learn to signal; it also gives rise to the phenomenon of linguistic drift. 1 Introduction2 Dynamic Signalling Games with Reinforcement Learning2.1 Introducing new states2.2 Swapping state–action pairs3 Discounting the Past3.1 Learning to signal in a dynamic world3.2 An unexpected outcome: linguistic drift4 ConclusionAppendix: A Markov Chain Analysis. (shrink)

Die Musikpädagogik als Disziplin begann sich erst Anfang des 19. Jahrhunderts zu konstituieren. Gleichwohl hat Johann Gottfried Herder zahlreiche musikpädagogische Ideen benannt und reflektiert. Als leidenschaftlicher Musikliebhaber und Pädagoge kreisten seine Gedanken in retrospektiver Ferne und interkultureller Weite, ohne theoriebildenden Anspruch für die Musikerziehung zu erheben. Dennoch wurde Herder häufig als Gewährsmann verschiedener ideologischer Perspektiven bemüht. Die Studie will sachlich, ehrlich und unbefangen aufräumen, indem sie erstens Herders Spuren zur Erziehung durch Musik gründlich folgt, zweitens Irrtümer sowie Missdeutungen aus dem (...) Weg räumt, um drittens Herder als Wegbereiter durch Dokumentation seiner immensen Rezeption zu würdigen. (shrink)

Here we prove that if T and T′ are strongly minimal theories, where T′ satisfies a certain property related to triviality and T does not, and T′ is model complete, then there is no computable embedding of Mod(T) into Mod(T′). Using this, we answer a question from [4], showing that there is no computable embedding of VS into ZS, where VS is the class of infinite vector spaces over Q, and ZS is the class of models of Th(Z, S). Similarly, (...) we show that there is no computable embedding of ACF into ZS, where ACF is the class of algebraically closed fields of characteristic 0. (shrink)

Evolutionary game theoretic accounts of justice attempt to explain our willingness to follow certain principles of justice by appealing to robustness properties possessed by those principles. Skyrms (1996) offers one sketch of how such an account might go for divide-the-dollar, the simplest version of the Nash bargaining game, using the replicator dynamics of Taylor and Jonker (1978). In a recent article, D'Arms et al. (1998) criticize his account and describe a model which, they allege, undermines his theory. I sketch a (...) theory of evolutionary explanations of justice which avoids their methodological criticisms, and develop a spatial model of divide-the-dollar with more robust convergence properties than the models of Skyrms (1996) and D'Arms et al. (1998). (shrink)

We extend results of Harizanov and Barker. For a relation R on a recursive structure /oA, we give conditions guaranteeing that the image of R in a recursive copy of /oA can be made to have arbitrary ∑α0 degree over Δα0. We give stronger conditions under which the image of R can be made ∑α0 degree as well. The degrees over Δα0 can be replaced by certain more general classes. We also generalize the Friedberg-Muchnik Theorem, giving conditions on a pair (...) of relations R and S under which the images of R and S can be made ∑α0 and independent over Δα0 in a recursive copy of /oA. (shrink)

It is certainly the case that morality governs the interactions that take place between individuals. But what if morality exists because of these interactions? This book, first published in 2007, argues for the claim that much of the behaviour we view as 'moral' exists because acting in that way benefits each of us to the greatest extent possible, given the socially structured nature of society. Drawing upon aspects of evolutionary game theory, the theory of bounded rationality, and computational models of (...) social networks, it shows both how moral behaviour can emerge in socially structured environments, and how it can persist even when it is not typically viewed as 'rational' from a traditional economic perspective. This book also provides a theory of how moral principles and the moral sentiments play an indispensable role in effective choice, acting as 'fast and frugal heuristics' in social decision contexts. (shrink)

In this paper, we give an example of a complete computable infinitary theory T with countable models ${\mathcal{M}}$ and ${\mathcal{N}}$ , where ${\mathcal{N}}$ is a proper computable infinitary extension of ${\mathcal{M}}$ and T has no uncountable model. In fact, ${\mathcal{M}}$ and ${\mathcal{N}}$ are (up to isomorphism) the only models of T. Moreover, for all computable ordinals α, the computable ${\Sigma_\alpha}$ part of T is hyperarithmetical. It follows from a theorem of Gregory (JSL 38:460–470, 1972; Not Am Math Soc 17:967–968, 1970) (...) that if T is a Π 1 1 set of computable infinitary sentences and T has a pair of models ${\mathcal{M}}$ and ${\mathcal{N}}$ , where ${\mathcal{N}}$ is a proper computable infinitary extension of ${\mathcal{M}}$ , then T would have an uncountable model. (shrink)

Jacobi held a position of unparalleled importance in late eighteenth and early nineteenth century intellectual history. This includes his role in bringing about the close of the Enlightenment, his central part in shaping the reception of Kant's philosophy and German idealism, and his influence on the development of Romanticism and existentialism.

Decision theory faces a number of problematic gambles which challenge it to say what value an ideal rational agent should assign to the gamble, and why. Yet little attention has been devoted to the question of what an ideal rational agent is, and in what sense decision theory may be said to apply to one. I show that, given one arguably natural set of constraints on the preferences of an idealized rational agent, such an agent is forced to be indifferent (...) among entire families of goods, and hence cannot choose among them. This result illustrates the dangers of speaking of the choices of an ?ideal rational agent? when one does not make precise the exact nature of the idealizing assumptions. The result may also be viewed as providing an upper bound on the kinds of idealizing assumptions which can be made for rational agents, beyond which the very concept of choice becomes attenuated. (shrink)

Name der Zeitschrift: Neue Zeitschrift für Systematische Theologie und Religionsphilosophie Jahrgang: 57 Heft: 1 Seiten: 138-154.

In the course of history, many individuals have the dubious honor of being remembered primarily for an eponym of which they would disapprove. How many are aware that Joseph-Ignace Guillotin actually opposed the death penalty? Another notable case is that of Maria Agnesi, an Italian woman of privileged, but not noble, birth who excelled at mathematics and philosophy during the eighteenth century. In her treatise of 1748, Instituzioni Analitiche, she provided a comprehensive summary of the current state of knowledge concerning (...) both integral calculus and differential equations. Later in life she was elected to the Bologna Academy of Sciences and, in 1762, was consulted by the University of Turin for an opinion on the work of an up-and-coming mathematician named Joseph-Louis Lagrange. (shrink)

The Pasadena game is an example of a decision problem which lacks an expected value, as traditionally conceived. Easwaran (2008) has shown that, if we distinguish between two different kinds of expectations, which he calls ‘strong’ and ‘weak’, the Pasadena game lacks a strong expectation but has a weak expectation. Furthermore, he argues that we should use the weak expectation as providing a measure of the value of an individual play of the Pasadena game. By considering a modified version of (...) the Pasadena game, I argue that weak expectations may provide a very poor measure of the value of an individual play of the game, and hence should not be used to value individual plays unless further information is taken into consideration. (shrink)

Let be a recursive structure, and let R be a recursive relation on . Harizanov isolated a syntactical condition which is necessary and sufficient for to have recursive copies in which the image of R is r.e. of arbitrary r.e. degree. We had conjectured that a certain extension of Harizanov's syntactical condition would be necessary and sufficient for to have recursive copies in which the image of R is ∑α0 of arbitrary ∑α0 degree, but this is not the case. Here (...) we give examples illustrating some restrictions on the possible ∑α0 degrees. In these examples, the image of R cannot be ∑α0 of degree d unless d possesses an “α-table”. (shrink)

Ash and Nerode [2] gave natural definability conditions under which a relation is intrinsically r. e. Here we generalize this to arbitrary levels in Ershov's hierarchy of Δmath image sets, giving conditions under which a relation is intrinsically α-r. e.

Early German Romanticism sought to respond to a comprehensive sense of spiritual crisis that characterised the late eighteenth century. The study demonstrates how the Romantics sought to bring together the new post-Kantian idealist philosophy with the inheritance of the realist Platonic-Christian tradition. With idealism they continued to champion the individual, while from Platonism they took the notion that all reality, including the self, participated in absolute being. This insight was expressed, not in the language of theology or philosophy, but through (...) aesthetics, which recognised the potentiality of all creation, including artistic creation, to disclose the divine. In explicating the religious vision of Romanticism, this study offers a new historical appreciation of the movement, and furthermore demonstrates its importance for our understanding of religion today. (shrink)

Platonism has played a central role in Christianity and is essential to a deep understanding of the Christian theological tradition. At times, Platonism has constituted an essential philosophical and theological resource, furnishing Christianity with an intellectual framework that has played a key role in its early development, and in subsequent periods of renewal. Alternatively, it has been considered a compromising influence, conflicting with the faith's revelatory foundations and distorting its inherent message. In both cases the fundamental importance of Platonism, as (...) a force which Christianity defined itself by and against, is clear. Written by an international team of scholars, this landmark volume examines the history of Christian Platonism from antiquity to the present day, covers key concepts, and engages issues such as the environment, natural science and materialism. (shrink)

In this wide-ranging conversation, Michael Hardt reflects on recent transformations within Empire. Several unique themes emerge concerning power and pedagogy as they intersect with subjectivity and global crisis. Drawing on the common in conjunction with the tradition of love in education uncovers a different path that attends to today’s real political, ecological, and social needs. Finally, a focus on collectivity points to a possible strategy—collective intellectuality—for educators to revise traditional notions of leadership to encourage more ethical, democratic, and sustainable futures. (...) Yet, what this looks like in practice remains for us to imagine. (shrink)

Appeals to human nature are ubiquitous, yet historically many have proven ill-founded. Why? How might frequent errors be remedied towards building a more robust and reliable scientific study of human nature? Our aim is neither to advance specific scientific or philosophical claims about human nature, nor to proscribe or eliminate such claims. Rather, we articulate through examples the types of errors that frequently arise in this field, towards improving the rigor of the scientific and social studies. We seek to analyze (...) such claims rhetorically, cognitively, and epistemically. Namely, how do we think about human nature? Claims about human nature, we show, are susceptible to widely exhibited deficits in cognitive tendencies such as framing, confirmation bias, satisficing, and teleological perspectives, as well as motivated reasoning. Such missteps foster methodological, empirical, and psychological mistakes and biases. Specifically, they promote the naturalizing error, whereby cultural ideology and values are projected onto an apparently objective description of nature. Concrete remedies are offered to aid scientists in conducting and reporting their research goals and findings more responsibly and effectively (relevant also to educators and other communicators who convey these findings publicly). Recommendations include acknowledging that human nature claims are often context-dependent, seeking multiple critical perspectives, and explicitly labeling uncertainties. (shrink)

At the very end of the 19th century, Gabriele Tarde wrote that all society was a product of imitation and innovation. This view regarding the development of society has, to a large extent, fallen out of favour, and especially so in those areas where the rational actor model looms large. I argue that this is unfortunate, as models of imitative learning, in some cases, agree better with what people actually do than more sophisticated models of learning. In this paper, I (...) contrast the behaviour of imitative learning with two more sophisticated learning rules (one based on Bayesian updating, the other based on the Nash-Brown-von Neumann dynamics) in the context of social deliberation problems. I show for two social deliberation problems, the Centipede game and a simple Lewis sender-receiver game, that imitative learning provides better agreement with what people actually do, thus partially vindicating Tarde. (shrink)

Cheap talk has often been thought incapable of supporting the emergence of cooperation because costless signals, easily faked, are unlikely to be reliable (Zahavi and Zahavi, 1997). I show how, in a social network model of cheap talk with reinforcement learning, cheap talk does enable the emergence of cooperation, provided that individuals also temporally discount the past. This establishes one mechanism that suffices for moving a population of initially uncooperative individuals to a state of mutually beneficial cooperation even in the (...) absence of formal institutions. (shrink)

One of the more recalcitrant issues in the philosophy of time concerns the question of temporal asymmetry. Some theorists, many of them, like Einstein, physicists, believe that time is fundamentally reversible. According to this view, the physical universe is indifferent to the direction of time; consequently, something like an arrow of time is held to be a human subjective imposition on an otherwise temporally isotropic world. Another position, held by Alfred North Whitehead and contemporary process philosophers, maintains that temporal asymmetry (...) is a primitive condition of the universe, and that therefore even the most basic physical processes, such as those occurring at the subatomic level, display a distinct temporal direction. Finally, the philosopher of time J.T. Fraser (1978) claims that temporal asymmetry is an emergent feature of the universe, appearing for the first time with biogenesis. According to Fraser, with the emergence of life comes a present, or “now”, a temporal dimension whose absence in more primitive levels of cosmic evolution prohibits the attribution of an arrow of time to any pre-biotic entity. (shrink)

Consider the problem of allocating a scarce resource to people. A fair decision procedure is one where each person has an equal chance of receiving the resource. An unfair decision procedure is one where the chances are not equal. Normally we think that, in an unfair decision procedure, that the correct way to redress the injustice is by rerunning the allocation using a fair decision procedure. In this paper, I show that this actually creates an overall bias favouring one person, (...) and solutions to this problem are counterintuitive, in that they typically involve introducing additional unfair elements into the situation. (shrink)

With the earliest known reference to angling with a fly dating from the Chou Dynasty, more than 2,300 years ago, it should come as no surprise that when asked to justify their passionate devotion to fly fishing, many anglers will refer to the rich and venerable literature the sport has generated. Ranging from Plutarch's references to Nile fishing in the Life of Antonius, to Pliny the Elder's Historia Naturalis, to the fifteenth century classic, Dame Julian Berner's The Treatyse of Fysshynge (...) wyth an Angle, to the sport's bible, the 17th century The Compleat Angler by Izaak Walton, to literary treatments in the work of authors such as John Donne, Gerard Manley Hopkins, William Butler Yeats, Ezra Pound and Ernest Hemingway, the wealth of literature devoted to fly fishing appears to be out of proportion to what is, ultimately, just a way of seducing an animal with a brain the size of a pea into inhaling a hook upon which some feathers, furs and tinsels have been lashed. What then, one may legitimately ask, is it about this sport that creates fanatical devotion on the part of its practitioners, who tend to regard it with such zeal and passion as is commonly reserved for art and religion? (shrink)

Rachlin's idea that altruism, like self-control, is a valuable, temporally extended pattern of behavior, suggests one way of addressing common problems in developing a rational choice explanation of individual altruistic behavior. However, the form of Rachlin's explicitly behaviorist account of altruistic acts suffers from two faults, one of which questions the feasibility of his particular behaviorist analysis.

This chapter contains section titled: Kin Selection Reciprocity Group Selection Coercion Mutualism Byproduct Mutualism Local Interactions References.